Author
Dr. Bhawna Kohli, Pradeep Kumar, Prashant Saraswat
Keywords
Immunization Coverage; Vaccine Effectiveness; Childhood Vaccination; Public Health Immunization Programs; Vaccine Uptake; Digital Health Interventions.
Abstract
Immunisation programmes represent one of the most effective interventions in global public health with regard to preventing infectious diseases and mitigating child mortality. Despite significant progress in global vaccination campaigns, disparities in immunisation rates continue due to socioeconomic disparities, healthcare access barriers, and vaccine hesitancy. This cross-sectional analytical study evaluates immunisation coverage and vaccine effectiveness among children using data collected on 268 children between 0–15 years of age visiting primary healthcare centres and immunisation clinics. Data on vaccination status, parental knowledge, healthcare access, and digital health interventions were collected through structured surveys and clinical immunisation history. Descriptive statistics, one-way ANOVA, and logistic regression determined variables contributing to vaccine uptake and efficacy. Findings indicate that good immunisation coverage is strongly linked with increased healthcare access (F=5.12, p=0.006), parental education (F=6.28, p=0.002), and systematic digital reminder systems (F=6.85, p=0.001). Digital health-based interventions including text-message reminders and electronic immunisation registries significantly increased vaccination compliance. Low parental education (β=0.42, p=0.002) and absence of reminder systems (β=0.39, p=0.003) were the strongest predictors of incomplete immunisation. Coverage gaps persist among groups with restricted healthcare access and lower socioeconomic status. The study highlights the paramount role of community-based health education, digital monitoring tools, and stronger immunisation infrastructure in increasing vaccine coverage and population health outcomes.
References
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[2] Carpiano, R. M., Polonijo, A. N., Gilbert, N., Cantin, L., & Dubé, E. (2019). Socioeconomic status differences in parental immunization attitudes and child immunization in Canada. Preventive Medicine, 123, 278–287.
[3] Catherine, S., Gupta, N., Gopi, E., & Swadhi, R. (2025). Enhancing Patient Engagement and Outcomes Through Digital Transformation: Machine Learning in Medical Marketing. In Impact of Digital Transformation on Business Growth and Performance (pp. 285–312). IGI Global.
[4] Costantino, C., Casuccio, A., & Restivo, V. (2020). Vaccination and vaccine effectiveness: A commentary. Vaccines, 8(3), 545.
[5] Devi, M., Manokaran, D., Sehgal, R. K., Shariff, S. A., & Vettriselvan, R. (2025). Precision Medicine, Personalized Treatment, and Network-Driven Innovations: Transforming Healthcare With AI. In AI for Large Scale Communication Networks (pp. 303–322). IGI Global.
[6] Elkin, N., Mohammed, A. K., Kılınçel, Ş., Soydan, A. M., Tanrıver, S. Ç., Çelik, Ş., & Ranganathan, M. (2025). Mental health literacy and happiness among university students: A social work perspective to promoting well-being. Frontiers in Psychiatry, 16, 1541316.
[7] Fairbrother, G., Freed, G. L., & Thompson, J. W. (2000). Measuring immunization coverage. American Journal of Preventive Medicine, 19(3), 78–88.
[8] Giannone, G., Giuliano, A. R., Bandini, M., Marandino, L., Raggi, D., Earle, W., & Necchi, A. (2022). HPV vaccination and HPV-related malignancies: impact, strategies and optimizations toward global immunization coverage. Cancer Treatment Reviews, 111, 102467.
[9] Markowitz, L. E., Drolet, M., Perez, N., Jit, M., & Brisson, M. (2018). Human papillomavirus vaccine effectiveness by number of doses: systematic review of data from national immunization programs. Vaccine, 36(32), 4806–4815.
[10] Odone, A., Ferrari, A., Spagnoli, F., Visciarelli, S., Shefer, A., Pasquarella, C., & Signorelli, C. (2015). Effectiveness of interventions that apply new media to improve vaccine uptake and vaccine coverage: a systematic review. Human Vaccines & Immunotherapeutics, 11(1), 72–82.
[11] Placzek, H., & Madoff, L. C. (2011). The use of immunization registry-based data in vaccine effectiveness studies. Vaccine, 29(3), 399–411.
[12] Rand, C. M., Brill, H., Albertin, C., Humiston, S. G., Schaffer, S., Shone, L. P., & Szilagyi, P. G. (2015). Effectiveness of centralized text message reminders on human papillomavirus immunization coverage for publicly insured adolescents. Journal of Adolescent Health, 56(5), S17–S20.
[13] Ranganathan, M., Jacob, A., Ashifa, K. M., Kumar, G. J., Anthony, M., Vijay, M., & Kumari, R. B. (2024). An investigation of the effects of chronic stress on attention in parents of children with neurodevelopmental disorders. Universal Journal of Public Health, 12(1), 37–50.
[14] Reifferscheid, L., Kiely, M. S., Lin, M. S. N., Libon, J., Kennedy, M., & MacDonald, S. E. (2023). Effectiveness of hospital-based strategies for improving childhood immunization coverage: A systematic review. Vaccine, 41(36), 5233–5244.
[15] Shanthi, H. J., Gokulakrishnan, A., Sharma, S., Deepika, R., & Swadhi, R. (2025). Leveraging Artificial Intelligence for Enhancing Urban Health: Applications, Challenges, and Innovations. In Nexus of AI, Climatology, and Urbanism for Smart Cities (pp. 275–306). IGI Global.
[16] Shefer, A., Briss, P., Rodewald, L., Bernier, R., Strikas, R., Yusuf, H., & Hinman, A. R. (1999). Improving immunization coverage rates: an evidence-based review of the literature. Epidemiologic Reviews, 21(1), 96–142.
[17] Shim, E., & Galvani, A. P. (2012). Distinguishing vaccine efficacy and effectiveness. Vaccine, 30(47), 6700–6705.
[18] Siddiqui, F. A., Padhani, Z. A., Salam, R. A., Aliani, R., Lassi, Z. S., Das, J. K., & Bhutta, Z. A. (2022). Interventions to improve immunization coverage among children and adolescents: a meta-analysis. Pediatrics, 149(Supplement 6), e2021053852D.
[19] Uskun, E., Uskun, S. B., Uysalgenc, M., & Yagız, M. (2008). Effectiveness of a training intervention on immunization to increase knowledge of primary healthcare workers and vaccination coverage rates. Public Health, 122(9), 949–958.
[20] Vakili, R., Ghazizadeh Hashemi, A., Khademi, G., Ajilian Abbasi, M., & Saeidi, M. (2015). Immunization coverage in WHO regions: a review article. Journal of Pediatric Perspectives, 3(2.1), 111–118.
[21] Vettriselvan, R., Ramya, R., Selvalakshmi, V., Jyothi, P., & Velmurugan, P. R. (2026). Empowering Patients through Knowledge: Educational Strategies in Rehabilitation. In Holistic Approaches to Health Recovery (pp. 263–290). IGI Global.
Received : 29 January 2026
Accepted : 26 March 2026
Published : 31 March 2026
DOI: 10.30726/ijmrss/v13.i1.2026.1323